Tech Platform Description

StopBleed1

Cross-linked Fibrin2

Miraqules is investing efforts to make its products ubiquitously available and be the most trusted and desired choice in the wound care domain. Miraqules’ clinically validated and patented technology has been designed to treat wounds of any severity, i.e., wounds ranging from minor abrasions to acute, severe traumatic injuries, and for use in intra-operative or post-operative hemostasis. The core technology of Miraqules is a scientifically designed manual process to produce fibrous compounds at room temperature using different biomaterial proportions, eliminating the conventional and expensive electrospinning technique. The innovative approach allows for the creation of fibrous compounds through a strong Coulomb interaction, which eliminates the need for any chemical crosslinking agent (as in the electrospinning technique), thereby reducing any potential toxicity or other undesirable effects.

Owing to their fibrous matrix-based architecture, these compounds possess a very high area-to-volume ratio, which considerably increases their absorption capacity (almost 30 times that of its initial dry weight) causing a quick concentration of the clotting factors on administration, accelerating the clotting cascade to work at its best. As the matrix has a net surface charge, these fibres form non-covalent bonds with the red blood cells and platelets that facilitate a stable clot formation. These concurrent events lead to the formation of a quick stable clot with a very high mechanical strength compared to the body’s self-formed clot.

StopBleed clotted blood3

Natural blood clot4

The similarity to the ECM and the use of GRAS materials make our products highly biocompatible and safe to use. Using our proprietary technology as a platform, a variety of products for applications, like burn wound management, chronic wound healing, anti-adhesive barriers, and superabsorbent sanitary pads are being conceptualized and a few of them are already in a developmental phase.